Association of Metformin Use and New-Onset International Classification of Diseases Coding of Neovascular Age-Related Macular Degeneration

Key Points

• New-onset neovascular age-related macular degeneration was less common among metformin users, with a notable discrepancy in incidence rates.
• The study found a 30% lower risk for developing this retinal condition in individuals taking metformin compared to non-users.
• Assessment using medical records and ICD coding methods highlights the association between the medication and visual pathology.
• These findings support the potential for metformin as a pharmacological intervention in managing retinal diseases.