Homocysteine levels and cancer risk in hypertensive adults across MTHFR C677T genotypes

Key Points

• Cancer risk increases with elevated homocysteine levels in hypertensive individuals, particularly in those with the MTHFR C677T genotype.
• Findings reveal a significant association between high homocysteine levels and cancer incidence, particularly in patients with the CC genotype.
• Observational analysis across various populations highlights the interplay of genetic and biochemical factors in cancer risk.
• This research may inform future strategies in cancer prevention, especially for individuals with hypertension.