What question did this study set out to answer?

This research aims to evaluate the impact of dutasteride and tamsulosin on kidney morphology in a rodent model.

March 13, 2026Open Access

The effects of dutasteride and tamsulosin, alone or in association, in the kidney morphology: experimental study in rats

Key Points

This research aims to evaluate the impact of dutasteride and tamsulosin on kidney morphology in a rodent model.
Conducted an experimental study using rats
Administered dutasteride and tamsulosin separately and in combination
Assessed kidney morphology and nephron integrity
Dutasteride led to more severe kidney damage than tamsulosin
Combined treatment resulted in significant nephron losses
Isolated tamsulosin caused less renal modifications compared to dutasteride

Abstract

The use of dutasteride and tamsulosin (isolated or in combination) promoted kidney damage with nephron losses in the rodent model. Animals that received dutasteride showed more severe renal modifications than those that received tamsulosin and combined therapy.

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Authors

Marcello Henrique Araujo Da Silva

Simone Gomes Ferreira

Bianca Martins Gregório

Journals

Acta Cirúrgica Brasileira

SHILAP Revista de lepidopterología

Actions

Institutions

Universidade do Estado do Rio de Janeiro

References and Citations

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Building similarity graph...

Analyzing shared references across papers

The effects of dutasteride and tamsulosin, alone or in association, in the kidney morphology: experimental study in rats

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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