乳がんサブタイプにおけるDNA損傷修復欠損を予測するゲノムスコアとBRCA1/2欠損の関連

Timmsら（木曜）はこの問題を研究した。

www.synapsesocial.com/papers/69d6ceb9733a2b54c8aa849a — DOI: https://doi.org/10.1186/s13058-014-0475-x

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. Prevalence of <i>BRCA</i> mutations in an unselected population of triple‐negative breast cancer· 2011 · 219 citations
2. Incidence and Outcome of <i>BRCA</i> Mutations in Unselected Patients with Triple Receptor-Negative Breast Cancer· 2011 · 602 citations
3. Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer· 2003 · 959 citations
4. Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents· 2012 · 681 citations
5. Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from <i>BRCA</i> Mutation Carriers· 2009 · 3,625 citations