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April 10, 2026Open Access

Characterization of Pulmonary Dysfunction in Systemic Juvenile Idiopathic Arthritis Using Xenon and Proton MRI

Key Points

To characterize pulmonary dysfunction in systemic juvenile idiopathic arthritis (SJIA) using advanced MRI techniques.
Utilized xenon and proton MRI to assess lung abnormalities in SJIA
Analyzed RBC/Membrane signals for pulmonary diffusion limitation
Explored potential for longitudinal monitoring of lung function changes
Identified specific pulmonary abnormalities associated with SJIA
Demonstrated RBC/Membrane as a promising indicator of diffusion limitation
Highlighted the capability of MRI for future phenotyping of SJIA-related lung issues

Abstract

Xenon and proton lung MRI can identify SJIA-LD-associated pulmonary abnormalities, with RBC/Membrane showing particular promise for characterization of pulmonary diffusion limitation in SJIA-LD. Future studies will evaluate lung MRI for SJIA-LD phenotyping and longitudinal monitoring of SJIA-associated lung function changes.

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Discussion

Authors

William J. Garrison

Matthew M. Willmering

Bilal I. Masokano

Journals

Pediatric Pulmonology

Actions

Institutions

University of Cincinnati

Children's Hospital of Philadelphia

Cincinnati Children's Hospital Medical Center

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Characterization of Pulmonary Dysfunction in Systemic Juvenile Idiopathic Arthritis Using Xenon and Proton MRI

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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