Management of ERCP Failure in Malignant Biliary Obstruction: Comparative Effectiveness and Safety of EUS ‐Guided Gallbladder Drainage Versus Choledocoduodenostomy

Key Points

• This research investigates the efficacy and safety of EUS-guided gallbladder drainage compared to choledocoduodenostomy in managing malignant biliary obstruction after failed ERCP.
• Compared EUS-guided gallbladder drainage (EUS-GBD) and choledocoduodenostomy (EUS-CDS) outcomes in patients with malignant biliary obstruction (MDBO).
• Assessed rates of efficacy and safety post-procedure.
• Included patients without previous cholecystectomy and with clear cystic duct patency.
• Both EUS-GBD and EUS-CDS showed comparable efficacy in MDBO management.
• The safety profiles of EUS-GBD and EUS-CDS were similarly favorable.
• EUS-GBD could be a simpler and safer alternative for suitable MDBO patients.