The role of Klotho protein in delaying cellular ageing through exercise intervention: SA - β - Gal activity and age-related metabolism

Key Points

• This research explores how the Klotho protein influences cellular ageing and metabolism through exercise.
• Examined the effects of exercise intervention on serum Klotho protein levels.
• Measured age-related changes in SA - β - Gal activity and gene methylation.
• Analyzed oxidative stress and lipid metabolism changes post-exercise.
• Exercise increased serum levels of Klotho protein.
• Found reductions in SA - β - Gal activity, indicating delayed cellular ageing.
• Improved oxidative stress markers and lipid metabolism were observed post-exercise.

Abstract