More than a symptom: itch as an independent clinical contributor in atopic dermatitis - a global-scale study on 15,223 patients

Key Points

• This research aims to assess the impact of pruritus on the quality of life for patients with atopic dermatitis.
• Conducted an international study involving 15,223 atopic dermatitis patients across 27 countries
• Utilized validated assessment tools such as ABS-A, SOL, and PUSH-D to measure pruritus and its effects
• Analyzed the correlation between pruritus severity and quality of life outcomes
• Severe pruritus is found to significantly impair daily activities and professional careers of patients
• Quality of life is notably affected due to pruritus, highlighting its role as an independent contributor to disease burden
• There is an urgent need for systematic evaluation and targeted management strategies for pruritus in clinical practice