Premalignant Pathomorphology of the Liver in Chronic Hepatitis C: Clinicopathological and Immunohistochemical Correlations

Key Points

• The central aim is to investigate the premalignant changes in liver pathology due to chronic hepatitis C.
• Analyzed liver tissue from patients with chronic hepatitis C
• Evaluated morphological changes microscopically
• Investigated immune-cell activity and fibrosis levels
• Findings show significant morphological alterations in liver tissue due to chronic hepatitis C
• Identified strong correlation between immune-cell activity and degree of liver fibrosis
• Detected increased activation of Kupffer and hepatic stellate cells in fibrotic livers