What question did this study set out to answer?

The aim is to evaluate SORD activity in red blood cells for rapid screening of SORD-related neuropathies.

April 25, 2026

Measurement of Red Blood Cell Sorbitol Dehydrogenase Activity for Fast Screening of SORD ‐Related Neuropathies

NMNicholas MoroHôpital Bichat-Claude-Bernard SFStanislas FrancoisHôpital Bichat-Claude-Bernard CGC. GrondinHôpital Bichat-Claude-Bernard

Key Points

The aim is to evaluate SORD activity in red blood cells for rapid screening of SORD-related neuropathies.
Direct measurement of sorbitol dehydrogenase activity in red blood cells (RBC)
Comparison with plasma or urine sorbitol levels using mass spectrometry
Clinical procedures incorporated for efficiency.
Enables fast screening for SORD-related neuropathies.
Offers a convenient alternative to traditional testing methods.
Facilitates quicker clinical decision-making.

Abstract

This test provides a useful alternative to measuring plasma or urine sorbitol with mass spectrometry, allowing clinicians to directly evaluate SORD activity in RBC. As a result, it enables quick and convenient screening for SORD-related neuropathies during standard clinical procedures.

AIに質問

Bookmark

View Full Paper