心不全における炎症

Murphyら（Sun,）は心不全に関するレビューを実施しました。抗炎症療法が評価されました。抗炎症病態生理で駆動される特定の心不全表現型に対して、標的型抗炎症療法が予後を改善する可能性があるが、これまでの臨床試験はほとんど成功していません。

www.synapsesocial.com/papers/69f178a0adb7394e289b4893 — DOI: https://doi.org/10.1016/j.jacc.2020.01.014

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. Maladaptive Role of IL-6 in Ischemic Acute Renal Failure· 2005 · 250 citations
2. TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II· 2002 · 427 citations
3. TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II· 2002 · 345 citations
4. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy· 2005 · 896 citations
5. Design of the GutHeart—Targeting Gut Microbiota to Treat Heart Failure—Trial: A Phase II, Randomized Clinical Trial