心肥大型心筋症患者389名を対象としたβ-ミオシン重鎖遺伝子の包括的解析

Driestら（Sun,）は心肥大型心筋症（n=389）における観察研究を実施した。MYH7変異と変異なしの群で診断時年齢（歳）（p=0.0002）を評価。MYH7変異を持つHCM患者はより若年（32.9歳対42.7歳、p=0.0002）で診断され肥大も強いが、1親等の家族における突然死頻度に差はなかった。

www.synapsesocial.com/papers/69f31e80b24eb58ef2fb05ac — DOI: https://doi.org/10.1016/j.jacc.2004.04.039

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