Supplementary Figure S1 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma

Key Points

• MAIN FINDING: RAS(ON) multi-selective inhibition significantly inhibits PDAC growth in tumor models.
• KEY EVIDENCE: The intervention led to reduced tumor volume in preclinical tests using implanted tumor models.
• APPROACH: The study utilized preclinical mouse models of pancreatic ductal adenocarcinoma for testing.
• SIGNIFICANCE: These findings indicate the potential of T-cell dependence in enhancing cancer treatment strategies for PDAC.

Abstract