Late-Stage Saturation of Drug Molecules

Liu et al. (Mon,) studied this question.

www.synapsesocial.com/papers/68e6f047b6db64358766ad15 — DOI: https://doi.org/10.1021/jacs.4c00807

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2· 2007 · 97 citations
2. Effects of 1-cyclohexyl- and 1-cyclohexyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on dopaminergic spontaneous discharge in nigral neurons of rats· 2016 · 4 citations
3. Synthesis of (+)-ribostamycin by catalytic, enantioselective hydroamination of benzene· 2022 · 33 citations
4. α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment