What question did this study set out to answer?

The aim is to develop an automated system for efficient exosome isolation from whole blood.

January 22, 2026

EV-Blade: an automated centrifugal-pneumatic cartridge for size- and affinity-based exosome isolation from whole blood

Key Points

The aim is to develop an automated system for efficient exosome isolation from whole blood.
Designed an automated centrifugal-pneumatic cartridge.
Focused on size- and affinity-based exosome isolation.
Tested the system using whole blood samples.
Successfully isolated exosomes with high purity.
Demonstrated effectiveness in cancer biomarker applications.
Improved efficiency compared to traditional methods.

Abstract

Extracellular vesicles (EVs), especially the exosome sized subset are increasingly exploited as minimally invasive cancer biomarkers. These small vesicles are abundant in biofluids and play crucial roles in intercellular communication...

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Authors

Lucas Poncelet

Keith Morton

Matthew Shiu

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Lab on a Chip

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EV-Blade: an automated centrifugal-pneumatic cartridge for size- and affinity-based exosome isolation from whole blood

Key Points

Abstract

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Authors

Journals

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References and Citations

Citation Network

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