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Changes in Myocardial Light Chain Amyloid Burden After Plasma Cell Therapy | Synapse
March 3, 2026
Open Access
Changes in Myocardial Light Chain Amyloid Burden After Plasma Cell Therapy
DB
Dominik C Benz
OC
Olivier F Clerc
SC
Sarah A M Cuddy
Brigham and Women's Hospital
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Key Points
Reduction in myocardial light chain amyloid burden indicates therapy effectiveness, with implications for heart function.
A significant decrease in amyloid burden was observed in patients following plasma cell therapy over six months.
The therapy assessment involved measuring amyloid levels using imaging techniques and biomarkers.
These findings support potential improvements in cardiac health, but further studies are needed for broader validation.
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Benz et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75debc6e9836116a283bf
https://doi.org/https://doi.org/10.5167/uzh-283376