Clinical, electrophysiological, and radiological clues in the transition to secondary progressive multiple sclerosis and evaluation of thalamus volume

Key Points

• Transitioning to secondary progressive multiple sclerosis is observed through various clinical indicators, including thalamus volume.
• Significant correlations between thalamus volume and the onset of secondary progressive multiple sclerosis were noted, with a specific focus on brain imaging.
• This analysis included both electrophysiological and radiological assessments to understand disease progression.
• The findings suggest essential clinical implications for early identification and monitoring of secondary progressive multiple sclerosis.