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ADMSC-derived exosomes promote diabetic wound healing by inhibiting neutrophil extracellular traps formation through delivering miR-92a-1-5p | Synapse
March 3, 2026
ADMSC-derived exosomes promote diabetic wound healing by inhibiting neutrophil extracellular traps formation through delivering miR-92a-1-5p
WL
Wei Li
The University of Texas Medical Branch at Galveston
HZ
Hong Zhang
Central South University
PB
Pengxing Bai
Shanxi Medical University
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Key Points
ADMSC-derived exosomes significantly reduce neutrophil extracellular traps formation, enhancing diabetic wound healing.
The study reports a key role for mir-92a-1-5p in mediating the effects of exosomes in wound repair processes.
Assessment using exosomal delivery systems demonstrates their potential in treating diabetic wounds effectively.
This indicates that further exploration of exosomal therapies could transform wound management strategies for diabetes.
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Li et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75f2ec6e9836116a2a5e5
https://doi.org/https://doi.org/10.1016/j.abb.2026.110755