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The multifaceted roles of G protein-coupled receptor C3aR1 in disease: From immunomodulation to cancer progression | Synapse
March 3, 2026
The multifaceted roles of G protein-coupled receptor C3aR1 in disease: From immunomodulation to cancer progression
JC
Jiayao Cui
FS
Fangyu Shen
CZ
Chenmiao Zhang
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Key Points
C3aR1 plays a critical role in immune modulation, impacting disease outcomes related to cancer.
The analysis reveals significant correlations between C3aR1 activity and various biomarkers linked to cancer progression.
Observational analysis reveals C3aR1's multifaceted influence across multiple disease contexts, emphasizing its relevance.
Understanding C3aR1's mechanisms could open pathways for innovative cancer therapies, highlighting the need for further research.
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Cui et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75f9ec6e9836116a2b1e4
https://doi.org/https://doi.org/10.1016/j.prp.2026.156386
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