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Exploring Novel Endocannabinoid Pathways in Sclerotic Chronic Graft-Versus-Host-Disease | Synapse
March 3, 2026
Exploring Novel Endocannabinoid Pathways in Sclerotic Chronic Graft-Versus-Host-Disease
SG
Sencer Göklemez
National Cancer Institute
SP
Steven Z. Pavletic
HC
Hyoyoung Choo‐Wosoba
National Institutes of Health
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Key Points
Chronic graft-versus-host disease shows a potential link to novel endocannabinoid pathways, highlighting new areas for treatment.
A significant finding includes altered immune response markers which may inform future therapies.
Assessment using clinical observations and biomarker profiling reveals intricate relationships between sclerosis and endocannabinoids.
Understanding these pathways may enable the development of targeted therapies in patients with chronic graft-versus-host disease.
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Göklemez et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760d9c6e9836116a2dfab
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.357
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