CAR-T cell Therapy Following Allogeneic Stem Cell Transplant: Clinical Outcomes and Toxicity Profile from a Single-Center Retrospective Cohort

Key Points

• CAR-T cell therapy shows variable clinical outcomes in post-transplant patients, indicating a need for careful monitoring.
• Among the assessed patients, 30% experienced severe toxicities associated with the treatment, raising safety concerns.
• Retrospective cohort analysis across a single center evaluated the effectiveness and side effects of CAR-T cell therapy.
• Findings call for further investigation into the long-term safety and effectiveness in this specific patient population.