Vδ2 T-cell cytotoxic polarity shift is associated with vascular dysfunction in unexplained recurrent miscarriage: A preliminary study

Key Points

• Cytotoxic polarity shift in Vδ2 T-cells correlates with vascular dysfunction.
• A significant 40% shift was observed in the cytotoxicity levels of Vδ2 T-cells among participants.
• Observational analysis focused on women experiencing recurrent miscarriage, identifying immune response mechanisms.
• Findings may inform future therapeutic strategies, emphasizing the need for further validation in larger cohorts.