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In silico evaluation of natural opioid ligands interaction and their therapeutic prospects in neuroinflammation | Synapse
March 3, 2026
Open Access
In silico evaluation of natural opioid ligands interaction and their therapeutic prospects in neuroinflammation
PG
Pratikkumar Gaglani
Banaras Hindu University
SS
Shalini Sharma
Banaras Hindu University
AS
Atul Srivastava
Indian Institute of Tropical Meteorology
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Key Points
The evaluation reveals potential therapeutic effects of opioid ligands in neuroinflammation through molecular pathways.
Key interactions identified include several natural ligands, suggesting promising therapeutic avenues with specific binding affinities.
In silico analysis utilizes molecular docking techniques to assess ligand interactions with neuroinflammatory markers and receptors.
These findings highlight new strategies for addressing neuroinflammation, calling for further exploration in clinical settings.
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Gaglani et al. (Tue,) studied this question.
synapsesocial.com/papers/69a761ddc6e9836116a2ff09
https://doi.org/https://doi.org/10.1007/s40203-026-00584-w