PCDSOS: a novel clinical predictive tool for screening primary ciliary dyskinesia in adult bronchiectasis patients—a multicenter derivation and external validation study

Key Points

• To evaluate the effectiveness of PCDSOS in screening for primary ciliary dyskinesia in adult bronchiectasis patients.
• Conducted a multicenter derivation and external validation study
• Compared PCDSOS with existing screening tools
• Analyzed cost-effectiveness of PCDSOS
• PCDSOS outperformed existing screening tools in identifying patients with PCD
• Demonstrated potential for cost-effective screening
• Highlights importance for preventing irreversible lung damage