What question did this study set out to answer?

To assess the clinical value of new biomarkers in evaluating thrombus formation and fibrinolytic activity in AMI patients undergoing PCI.

March 14, 2026Open Access

Four new markers of early thrombotic molecules and thromboelastography in prognostic evaluation of AMI patients undergoing PCI

Key Points

To assess the clinical value of new biomarkers in evaluating thrombus formation and fibrinolytic activity in AMI patients undergoing PCI.
Evaluated biomarkers: TM, TAT, PIC, and t-PAIC.
Used thromboelastography (TEG) to monitor coagulation process in whole blood.
Conducted analysis on AMI patients undergoing percutaneous coronary intervention (PCI).
Biomarkers showed potential for refined thrombus formation assessment.
TEG provided insights for optimizing antiplatelet therapy.
Markers correlated with coagulation monitoring results, indicating prognostic value.

Abstract

Based on the available evidence, we conclude that the biomarkers-TM, TAT, PIC, and t-PAIC-demonstrate potential clinical value in providing a more refined assessment of thrombus formation and fibrinolytic activity and TEG provides an important basis for optimizing antiplatelet therapy by dynamically monitoring the coagulation process in whole blood.

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Authors

Weisha Sun

Yi Gao

Wei Sun

Journals

The Egyptian Heart Journal

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Institutions

Shanxi Medical University

Shaanxi Provincial People's Hospital

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Four new markers of early thrombotic molecules and thromboelastography in prognostic evaluation of AMI patients undergoing PCI

Key Points

Abstract

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Discussion

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Journals

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Institutions

References and Citations

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