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Cadherin-mediated differentiation of MSC-derived liver organoids: sequencing at day 7 | Synapse

April 1, 2026Open Access

Cadherin-mediated differentiation of MSC-derived liver organoids: sequencing at day 7

Key Points

This research aims to explore how cadherin affects the differentiation of mesenchymal stem cell (MSC) aggregates into liver organoids.
Used cadherin-functionalized PLGA microspheres for differentiation
Performed RNA sequencing on day 7 of organoid development
Analyzed gene expression profiles of differentiated organoids
Identified key genes involved in liver differentiation
Demonstrated successful formation of liver-like structures
Showed enhanced organoid development compared to control conditions

Abstract

RNA Sequencing results of MSC aggregates differentiated into liver organoids on day 7 using cadherin-functionalized PLGA microspheres

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Cite This Study

秦政(Jun Yang) (Thu,) studied this question.

synapsesocial.com/papers/69ccb63f16edfba7beb87f61 https://doi.org/https://doi.org/10.26036/cnp0009129

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