Does intravenous cangrelor act as a safe and effective rescue therapy for acute thrombosis during neuroendovascular procedures?
Patients experiencing acute thrombosis after cerebral aneurysm embolization (limited case series)
Intravenous cangrelor as rescue therapy
Safety and efficacy (emergency thrombolysis capability)
Intravenous cangrelor may serve as an attractive rescue agent for acute thrombosis during neuroendovascular procedures due to its rapid onset, reversible inhibition, and short half-life.
In this limited series, cangrelor was found to be a safe and effective IV platelet inhibitor with emergency thrombolysis capability after cerebral aneurysm embolization. Cangrelor is an attractive rescue agent due to its rapid onset, reversible P2Y12 inhibition, and extremely short half-life (on/off effect). https://thejns.org/doi/10.3171/CASE25930.
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Mehlika Esra Sahin
Ailsa Fulton
Suniksha Deshpande
Journal of Neurosurgery Case Lessons
Duke University
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Sahin et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69d893eb6c1944d70ce04da6 — DOI: https://doi.org/10.3171/case25930