Enhanced therapeutic potential of folic acid-tagged targeted liposomal quercetin (Lipo-Que) over Free-Que in Benzo a pyrene-induced lung cancer in mice

Key Points

• This research aims to compare the efficacy of folic acid-tagged liposomal quercetin to free quercetin in lung cancer treatment.
• Utilized a mouse model of lung cancer induced by benzo [a] pyrene.
• Administered folic acid-tagged liposomal quercetin and free quercetin for comparison.
• Measured therapeutic outcomes and effects on tumor development.
• Lipo-Que showed superior therapeutic efficacy compared to Free-Que.
• Lipo-Que demonstrated better targeted delivery to lung tissues.
• The findings support Lipo-Que as a promising treatment option for lung cancer.

Abstract