What question did this study set out to answer?

The aim is to develop nanoporous hydroxyapatite microparticles for treating chronic inflammatory diseases of small joints.

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April 10, 2026Open Access

Porous hydroxyapatite microparticles loaded with 169 Er for treatment of chronic inflammatory disease of small joints: harnessing mechanochemistry for synthesis of an advanced biomaterial

Key Points

The aim is to develop nanoporous hydroxyapatite microparticles for treating chronic inflammatory diseases of small joints.
Synthesis of HA microparticles using a solid-state mechanochemical approach.
Utilization of a d(+)-glucose template for nanopore formation.
Successful synthesis of nanoporous hydroxyapatite microparticles.
Potential applicability of the developed biomaterial for targeted treatment.

Abstract

In the present study, nanoporous hydroxyapatite microparticles (HA MPs) were synthesized using a d (+)-glucose template mediated solid state mechanochemical approach.

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Authors

Sourav Patra

Bhabha Atomic Research Centre

K. V. Vimalnath

Bhabha Atomic Research Centre

Srinivasu Kancharlapalli

Journals

RSC Advances

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Institutions

Bhabha Atomic Research Centre

Homi Bhabha National Institute

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Cite this study

Patra et al. (Thu,) studied this question.

synapsesocial.com/papers/69d894ce6c1944d70ce05b67 — DOI: https://doi.org/10.1039/d5ra09444e

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Recent progress on biomedical applications of functionalized hollow hydroxyapatite microspheres· 2021 · 22 citations
Mechanochemical synthesis of intermetallic compounds· 2001 · 55 citations
Mechanochemical synthesis of highly porous materials· 2020 · 321 citations
Post-radiosynovectomy imaging utilizing Erbium-169 citrate· 2019 · 2 citations
FTIR spectroscopic, thermal and XRD characterization of hydroxyapatite from new natural sources· 2011 · 181 citations

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Recent progress on biomedical applications of functionalized hollow hydroxyapatite microspheres· 2021 · 22 citations
Mechanochemical synthesis of intermetallic compounds· 2001 · 55 citations
Mechanochemical synthesis of highly porous materials· 2020 · 321 citations
Post-radiosynovectomy imaging utilizing Erbium-169 citrate· 2019 · 2 citations
FTIR spectroscopic, thermal and XRD characterization of hydroxyapatite from new natural sources· 2011 · 181 citations

Porous hydroxyapatite microparticles loaded with 169 Er for treatment of chronic inflammatory disease of small joints: harnessing mechanochemistry for synthesis of an advanced biomaterial

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Also consider