DNA Alterations in the Upstream Region of Exon 1 of OSBPL10 in Northern Thai Patients with Diffuse Large B-Cell Lymphoma

Key Points

• This research aims to explore genetic variations in the OSBPL10 gene and their relationship with clinical parameters in diffuse large B-cell lymphoma (DLBCL).
• Analyzed DNA alterations in the upstream region of OSBPL10
• Assessed clinical parameters related to DLBCL
• Investigated the link between regulatory-region SNPs and extranodal involvement
• Identified variations upstream of OSBPL10 associated with clinical parameters
• Found a significant association between SNPs and extranodal involvement
• Highlighted the prognostic potential of genetic diversity in lymphomas

Abstract