Impression cytology is a feasible, minimally invasive diagnostic tool for OSSN that can identify dysplastic changes and guide clinical management in resource-limited settings. While it cannot definitively diagnose stromal invasion and histopathological confirmation remains necessary when invasion is suspected, IC serves as a useful screening and monitoring modality in rural healthcare environments. Larger prospective studies are needed to validate these preliminary findings.
Agarwal et al. (Tue,) studied this question.