Maternal hypoxia-induced neurodevelopmental disorder-like behaviours point to morphological and/or functional deficits in excitatory pyramidal neurones, potentially causing excitatory/inhibitory imbalance in the anterior cingulate cortex. Enhancing excitatory synaptic response may represent a novel therapeutic strategy for hypoxia-related neurodevelopmental disorders.
Tokudome et al. (Wed,) studied this question.