Economic Burden of Recurrence in Early-Stage Hepatocellular Carcinoma Treated with Surgical Resection or Local Ablation in the United States: A Retrospective Analysis of Surveillance, Epidemiology and End Results–Medicare Data

Key Points

• This research examines the healthcare resource utilization and costs associated with disease recurrence in early-stage hepatocellular carcinoma (HCC).
• Used Medicare data for a retrospective analysis of early-stage HCC cases
• Compared healthcare resource utilization between recurrence and non-recurrence groups
• Analyzed costs associated with surgical resection and local ablation procedures
• Patients with disease recurrence faced significantly higher total healthcare costs
• Increased healthcare resource utilization was observed among patients withrecurrence compared to those who remained recurrence free
• Findings highlighted the economic impact of recurrent disease on healthcare systems

Abstract