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Colon cancers with high-frequency microsatellite instability have clinical and pathological features that distinguish them from microsatellite-stable tumors. We investigated the usefulness of microsatellite-instability status as a predictor of the benefit of adjuvant chemotherapy with fluorouracil in stage II and stage III colon cancer.
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Ribic et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69def4ec40ea065679559d5b — DOI: https://doi.org/10.1056/nejmoa022289
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
Christine Ribic
Daniel J. Sargent
Malcolm J. Moore
New England Journal of Medicine
University of Toronto
Brigham and Women's Hospital
The University of Texas MD Anderson Cancer Center
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