Substantial institutional variation in antibody prevalence suggests need for site-specific approaches to testing and prophylactic matching. High co-occurrence of auto- and alloantibodies, antibody immunogenicity patterns, and antigen-antibody discordances support the need for further research and consideration of refined testing and/or matching strategies beyond the current Rh and K standard.
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Covington et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69df2b65e4eeef8a2a6b063e — DOI: https://doi.org/10.1111/trf.70213
Mischa L. Covington
Elizabeth S. Allen
Stella T. Chou
Transfusion
University of Michigan
University of Pennsylvania
University of California, San Diego
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