Expanded peripheral CD62L low inflammatory eosinophils in pediatric thunderstorm‐related asthma exacerbations: A single‐center analysis

Key Points

• This research aims to evaluate the role of CD62L low inflammatory eosinophils in thunderstorm-related asthma exacerbations in children.
• Single-center analysis of circulating eosinophils in children during thunderstorms
• Assessment of CD62L expression levels on inflammatory eosinophils
• Evaluated cytokine responsiveness and activation status
• Increased levels of CD62L low eosinophils observed in asthma exacerbations during thunderstorms
• These eosinophils displayed heightened activation and cytokine responsiveness
• Findings suggest a primed type-2 inflammatory profile in affected children

Abstract