Chlorhexidine is extensively utilized as a skin antiseptic in routine clinical practice. In recent years, reports of life-threatening hypersensitivity reactions induced by chlorhexidine have been increasing progressively. Nevertheless, severe allergic events attributable to chlorhexidine-containing skin disinfectants are frequently misdiagnosed in clinical settings. Herein, we present a pediatric case with recurrent severe allergic reactions following exposure to chlorhexidine-based skin disinfection. This report aims to raise clinicians' awareness of chlorhexidine hypersensitivity.
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Yujing Zhao
Yingqian Zhang
Juncong Kang
Frontiers in Allergy
Hospital of Hebei Province
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Zhao et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69fd7cd4bfa21ec5bbf05bfb — DOI: https://doi.org/10.3389/falgy.2026.1812841