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Reply to: Rethinking Intra-Arrest Thrombolysis: The Role of Patient Selection and Timing | Synapse
May 16, 2026
Open Access
Reply to: Rethinking Intra-Arrest Thrombolysis: The Role of Patient Selection and Timing
SO
Shinichiro Ohshimo
Hiroshima University
KC
Keith Couper
Warwick Hospital
BB
B. W. Böttiger
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Key Points
This reply aims to clarify the critical factors of patient selection and timing in intra-arrest thrombolysis.
Analytical discussion of existing literature on intra-arrest thrombolysis
Evaluation of patient selection criteria
Assessment of timing implications for thrombolytic interventions.
Timely thrombolysis improves survival rates and neurological outcomes in selected patients.
Patient characteristics significantly influence the effectiveness of thrombolysis during arrest.
Better protocols and timing recommendations could enhance current treatment outcomes.
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Ohshimo et al. (Fri,) studied this question.
synapsesocial.com/papers/6a080e2ba487c87a6a40daeb
https://doi.org/https://doi.org/10.1016/j.resplu.2026.101363