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Supplementary Figure S1 Expression levels of miR-196b-5p in different tumor stages and tumor grade. (A-B) In cohort 1, miR-196b-5p expression decreased with (A) higher tumor stage, whereas no difference could be observed for (B) tumor grade. (C-D) In cohort 2, (C) stage IV tumors and (D) high grade tumors showed the lowest levels of miR-196b-5p. Supplementary Figure S2 Kaplan-Meier curve for 5-year overall survival in tumor stage II/III patients in (A) cohort 1 (n=51) and (B) cohort 2 (n=122). In both cohorts, low miR-196b-5p expression levels were associated with poor clinical outcome (p
Stiegelbauer et al. (Wed,) studied this question.