Sequential electroporation and biomimetic mineralization on an E. coli biotemplate: green synthesis of functional porous hollow calcium phosphate capsules

Key Points

• The research aims to develop a new method for creating structured calcium phosphate capsules using E. coli as a biotemplate.
• Utilized E. coli as a biotemplate for capsule formation
• Implemented sequential electroporation for enhanced porosity
• Conducted biomimetic mineralization to create capsules
• Tested co-loading of multiple metal oxide nanoparticles within the capsules
• Successfully produced porous hollow calcium phosphate capsules (PHCPCs) using the proposed method
• Demonstrated the ability to co-load multiple metal oxide nanoparticles into the capsules
• Confirmed biosafety and structural integrity of the produced capsules