All patients with acute myeloid leukemia and FLT3-ITD should be transplanted in first remission. Also in the era of tyrosine kinase inhibitors? – the CON

Key Points

• Examine the need for transplantation in FLT3-ITD positive acute myeloid leukemia patients during first remission.
• Discuss the role of transplantation in treatment plans
• Evaluate the impact of tyrosine kinase inhibitors on outcomes
• Analyze current clinical practices and recommendations
• Highlights that transplantation could enhance remission rates
• Suggests that tyrosine kinase inhibitors may change standard treatment approaches
• Recommends reevaluating transplantation criteria for newer therapies