Dual NIR-I Excitation and Emission-Based Thermometry and pH-Responsive Drug Delivery Using NaYF4:Yb,Er@SiO2-Folic Acid Conjugates

Key Points

• The central aim is to create materials that combine drug delivery with temperature measurement for medical use.
• Synthesis of NaYF4:Yb,Er particles with cuboidal structure.
• Coating with SiO2 to enhance properties.
• Conjugation with folic acid for targeted delivery.
• Successful creation of dual NIR-I responsive particles.
• Demonstrated effectiveness in drug delivery based on pH levels.
• Potential for simultaneous diagnostic and therapeutic applications.