Reduced drying times enable rapid paper spray analysis of whole blood for clinical toxicology

Key Points

• This research aims to evaluate whether reducing drying times for whole blood spots affects the performance of paper spray ionisation-mass spectrometry in toxicology.
• Compared drying times of 10 minutes and 60 minutes for whole blood spots.
• Used paper spray ionisation-mass spectrometry for analysis.
• Evaluated performance in terms of identification and quantitation.
• Found equivalent performance at both drying times.
• Achieved confirmatory toxicology results in 15 minutes with reduced drying times.