A bi-functional pH-responsive chip with a soft hydrogel-supported 3D-like renal tumor model for sustained drug delivery

Key Points

• To develop a bi-functional chip for controlled drug delivery using a 3D renal tumor model.
• Created a pH-sensitive chip
• Integrated a soft hydrogel-based 3D renal tumor model
• Tested for controlled drug delivery capabilities
• Demonstrated sustained release of anticancer drugs
• Showed effective drug delivery in the 3D tumor model
• Confirmed pH-responsiveness in drug release patterns