Integrating systemic therapy into larynx preservation: Lessons from 3 decades of progress

Key Points

• The aim is to evaluate the role of systemic therapy in larynx preservation over the years and its impact on patient outcomes.
• Overview of studies on systemic therapy and larynx preservation
• Analysis of 20-year outcomes reported by Cunha et al.
• Contextualization of previous practice-changing studies
• Systemic therapy demonstrates significant efficacy in preserving larynx function.
• Cumulative practice-changing studies highlight the importance of systemic therapy in treatment decisions.
• The findings support the integration of systemic therapy for improved outcomes in organ preservation.