Comparison of liposomal bupivacaine and bupivacaine hydrochloride intercostal nerve blocks for postoperative analgesia after thoracic surgery: a multicenter, randomized, three arms trial protocol

Key Points

• This research aims to compare the effectiveness of liposomal bupivacaine versus bupivacaine hydrochloride for managing postoperative pain after thoracic surgery.
• Multicenter, randomized trial design
• Participants receive either liposomal bupivacaine or bupivacaine hydrochloride for intercostal nerve blocks
• Assessment of postoperative analgesia outcomes
• Expected differences in pain control between both types of bupivacaine
• Evaluation of side effects and overall patient satisfaction