To explore an efficient method for C3 alkylation of indoles and oxindoles using hydrogen borrowing.
Employed a Cp*Ir(iii) catalyst
Utilized an atom-economical approach
Followed an environmentally benign strategy
Successfully developed C3-substituted indole and oxindole scaffolds
Achieved high efficiency in the alkylation process
Demonstrated significant atom economy in the reactions
Abstract
C3-substituted indole or oxindole scaffolds have been developed using an ADC strategy with a highly efficient, atom-economical, and environmentally benign approach.