Endovascular administration and magnetic retention of nanocapsules for improved brain delivery in large cerebral vascular models

Key Points

• This research aims to enhance brain delivery of therapeutic agents using endovascular and magnetic strategies.
• Utilized endovascular techniques for delivery.
• Employed magnetic retention to improve retention of nanocapsules.
• Tested in large cerebral vascular models.
• Demonstrated improved focal delivery of nanocapsules in the brain.
• Showed increased retention time at targeted sites.
• Enhancements indicate potential for better therapeutic outcomes.