Combined polyphenols in Psidium guajava-citrus limon leaf extract attenuate fructose-induced cardiac injury by modulating metabolic and oxidative stress pathways in rats. | Synapse
Combined polyphenols in Psidium guajava-citrus limon leaf extract attenuate fructose-induced cardiac injury by modulating metabolic and oxidative stress pathways in rats.
Key Points
The aim is to investigate the effects of combined polyphenols from guava and lemon leaves on fructose-induced cardiac injury in rats.
Administered extract of Psidium guajava and citrus limon leaves to rats.
Induced cardiac stress using fructose.
Measured biomarkers for oxidative stress and cardiac injury.
Significant reduction in markers of cardiac injury in treated rats.
Improved metabolic function observed in the experimental group.
Reduced oxidative stress levels compared to fructose-only group.
Abstract
The combined lemon-guava leaf extract alleviates fructose-induced cardiac stress, demonstrating potential as a plant-based therapeutic agent for metabolic and cardiovascular protection.