Synthesis of 2-Furanyl Quinolines via Zinc-Catalyzed Cascade Cyclization of Enynones with Anthranils

Key Points

• The study aims to synthesize 2-furanyl quinolines using a zinc-catalyzed reaction involving enynones and anthranils.
• Conducted zinc(II)-catalyzed cascade cyclization
• Utilized enynones as substrates
• Incorporated anthranils for product formation
• Analyzed yields up to 91%
• Achieved synthesis of 2-furanyl quinolines in yields up to 91%
• Demonstrated effective ring-opening and tandem cyclization reactions
• Mechanistic insights provided for the reaction pathway